IFN-γ-inducible protein of 10 kDa upregulates the effector functions of eosinophils through β(2 )integrin and CXCR3

BACKGROUND: Eosinophils play an important role in the pathogenesis of bronchial asthma and its exacerbation. Recent reports suggest the involvement of IFN-γ-inducible protein of 10 kDa (IP-10) in virus-induced asthma exacerbation. The objective of this study was to examine whether CXCR3 ligands incl...

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Autori principali: Takaku, Yotaro, Nakagome, Kazuyuki, Kobayashi, Takehito, Hagiwara, Koichi, Kanazawa, Minoru, Nagata, Makoto
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3215664/
https://ncbi.nlm.nih.gov/pubmed/22004287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-12-138
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