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Proteoform-Specific Protein Binding of Small Molecules in Complex Matrices
Characterizing the specific binding between protein targets and small molecules is critically important for drug discovery. Conventional assays require isolation and purification of small molecules from complex matrices through multi-step chromatographic fractionation which may alter their original...
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| Publicado no: | ACS Chem Biol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5315634/ https://ncbi.nlm.nih.gov/pubmed/28001351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b01018 |
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