Increased plasma levels of circulating cell-free mitochondrial DNA in suicide attempters: associations with HPA-axis hyperactivity

Preclinical data suggest that chronic stress may cause cellular damage and mitochondrial dysfunction, potentially leading to the release of mitochondrial DNA (mtDNA) into the bloodstream. Major depressive disorder has been associated with an increased amount of mtDNA in leukocytes from saliva sample...

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Détails bibliographiques
Publié dans:Transl Psychiatry
Auteurs principaux: Lindqvist, D, Fernström, J, Grudet, C, Ljunggren, L, Träskman-Bendz, L, Ohlsson, L, Westrin, Å
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
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Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5315562/
https://ncbi.nlm.nih.gov/pubmed/27922635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2016.236
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