Interleukin-15 promotes intestinal dysbiosis with butyrate deficiency associated with increased susceptibility to colitis

Dysbiosis resulting in gut-microbiome alterations with reduced butyrate production are thought to disrupt intestinal immune homeostasis and promote complex immune disorders. However, whether and how dysbiosis develops before the onset of overt pathology remains poorly defined. Interleukin-15 (IL-15)...

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Detalhes bibliográficos
Publicado no:ISME J
Main Authors: Meisel, Marlies, Mayassi, Toufic, Fehlner-Peach, Hannah, Koval, Jason C, O'Brien, Sarah L, Hinterleitner, Reinhard, Lesko, Kathryn, Kim, Sangman, Bouziat, Romain, Chen, Li, Weber, Christopher R, Mazmanian, Sarkis K, Jabri, Bana, Antonopoulos, Dionysios A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5315477/
https://ncbi.nlm.nih.gov/pubmed/27648810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ismej.2016.114
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