Interleukin-15 promotes intestinal dysbiosis with butyrate deficiency associated with increased susceptibility to colitis

Dysbiosis resulting in gut-microbiome alterations with reduced butyrate production are thought to disrupt intestinal immune homeostasis and promote complex immune disorders. However, whether and how dysbiosis develops before the onset of overt pathology remains poorly defined. Interleukin-15 (IL-15)...

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Bibliografiska uppgifter
I publikationen:ISME J
Huvudupphovsmän: Meisel, Marlies, Mayassi, Toufic, Fehlner-Peach, Hannah, Koval, Jason C, O'Brien, Sarah L, Hinterleitner, Reinhard, Lesko, Kathryn, Kim, Sangman, Bouziat, Romain, Chen, Li, Weber, Christopher R, Mazmanian, Sarkis K, Jabri, Bana, Antonopoulos, Dionysios A
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2017
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Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5315477/
https://ncbi.nlm.nih.gov/pubmed/27648810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ismej.2016.114
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