CD28/B7 deficiency attenuates systolic overload-induced congestive heart failure, myocardial and pulmonary inflammation, and activated T-cell accumulation in the heart and lungs

The inflammatory response regulates congestive heart failure (CHF) development. T-cell activation plays an important role in tissue inflammation. We postulate that CD28 or B7 deficiency inhibits T-cell activation and attenuates CHF development by reducing systemic, cardiac and pulmonary inflammation...

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Pubblicato in:Hypertension
Autori principali: Wang, Huan, Kwak, Dongmin, Fassett, John, Hou, Lei, Xu, Xin, Burbach, Brandon J., Thenappan, Thenappan, Xu, Yawei, Ge, Jun-bo, Shimizu, Yoji, Bache, Robert J., Chen, Yingjie
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314944/
https://ncbi.nlm.nih.gov/pubmed/27432861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.116.07579
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