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Synthesis of some novel pyrazolo[3,4-d] pyrimidin-4(5H)-one derivatives as potential antimicrobial agent

OBJECTIVES: The aim of the present work was to synthesize a novel series of pyrazolo[3,4-d]pyrimidin-4(5H)-one derivatives and evaluate their in vitro antimicrobial activity. METHODS: Cyclization of an ortho-amino ester of 1-(2,4-dinitrophenyl)pyrazole with various aliphatic/aromatic nitriles under...

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Bibliographic Details
Published in:J Pharm Bioallied Sci
Main Authors: Sureja, Dipen K., Dholakia, Sandip P., Vadalia, Kantilal R.
Format: Artigo
Language:Inglês
Published: Medknow Publications & Media Pvt Ltd 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314832/
https://ncbi.nlm.nih.gov/pubmed/28216957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0975-7406.199337
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