A nondeletional mechanism of peripheral tolerance in T-cell receptor transgenic mice.
To investigate tolerance to extrathymic self molecules, we produced two groups of transgenic mice: one expressed the major histocompatibility complex molecule H-2Kb in pancreatic beta cells, and the other expressed rearranged T-cell receptor genes encoding an anti-H-2Kb receptor. The transgenic T-ce...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53147/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1662395/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.24.11421 |
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