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Urocortin suppresses endometrial cancer cell migration via CRFR2 and its system components are differentially modulated by estrogen

Urocortin (UCN1) peptide shares structural and functional homology with corticotropin‐releasing factor (CRF). UCN1 is significantly reduced in endometrial adenocarcinoma compared to healthy controls. However, there are no data which evaluate the effects of UCN1 in the endometrium, or how it is modul...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Owens, Gemma L., Lawrence, Kevin M., Jackson, Tom R., Crosbie, Emma J., Sayan, Berna S., Kitchener, Henry C., Townsend, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5313640/
https://ncbi.nlm.nih.gov/pubmed/28109061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.967
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