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Urocortin suppresses endometrial cancer cell migration via CRFR2 and its system components are differentially modulated by estrogen

Urocortin (UCN1) peptide shares structural and functional homology with corticotropin‐releasing factor (CRF). UCN1 is significantly reduced in endometrial adenocarcinoma compared to healthy controls. However, there are no data which evaluate the effects of UCN1 in the endometrium, or how it is modul...

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Dades bibliogràfiques
Publicat a:Cancer Med
Autors principals: Owens, Gemma L., Lawrence, Kevin M., Jackson, Tom R., Crosbie, Emma J., Sayan, Berna S., Kitchener, Henry C., Townsend, Paul A.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5313640/
https://ncbi.nlm.nih.gov/pubmed/28109061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.967
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