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Pigment epithelium-derived factor, a non-inhibitory serine protease inhibitor, is renoprotective by inhibiting the Wnt pathway
Pigment epithelium-derived factor (PEDF) expression is down- regulated in the kidneys of diabetic rats and delivery of PEDF suppressed renal fibrotic factors in these animals. PEDF has multiple functions including anti-angiogenic, anti-inflammatory and anti-fibrotic activities. Since the mechanism u...
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| Publicat a: | Kidney Int |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5313326/ https://ncbi.nlm.nih.gov/pubmed/27914705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2016.09.036 |
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