G-protein-coupled receptor genes as protooncogenes: constitutively activating mutation of the alpha 1B-adrenergic receptor enhances mitogenesis and tumorigenicity.

Lignende værker

• Regions of the alpha 1-adrenergic receptor involved in coupling to phosphatidylinositol hydrolysis and enhanced sensitivity of biological function.
  af: Cotecchia, S, et al.
  Udgivet: (1990)
• A constitutively active mutant of the alpha 1B-adrenergic receptor can cause greater agonist-dependent down-regulation of the G-proteins G9 alpha and G11 alpha than the wild-type receptor.
  af: Lee, T W, et al.
  Udgivet: (1996)
• Molecular cloning and expression of the cDNA for the hamster alpha 1-adrenergic receptor.
  af: Cotecchia, S, et al.
  Udgivet: (1988)
• Phorbol esters promote alpha 1-adrenergic receptor phosphorylation and receptor uncoupling from inositol phospholipid metabolism.
  af: Leeb-Lundberg, L M, et al.
  Udgivet: (1985)
• Mutation of Pro-258 in transmembrane domain 6 constitutively activates the G protein-coupled alpha-factor receptor.
  af: Konopka, J B, et al.
  Udgivet: (1996)