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Comparison of whole genome amplification techniques for human single cell exome sequencing
BACKGROUND: Whole genome amplification (WGA) is currently a prerequisite for single cell whole genome or exome sequencing. Depending on the method used the rate of artifact formation, allelic dropout and sequence coverage over the genome may differ significantly. RESULTS: The largest difference betw...
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| Pubblicato in: | PLoS One |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5313163/ https://ncbi.nlm.nih.gov/pubmed/28207771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171566 |
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