Targeting TRAF3IP2 by Genetic and Interventional Approaches Inhibits Ischemia/Reperfusion-induced Myocardial Injury and Adverse Remodeling

Re-establishing blood supply is the primary goal for reducing myocardial injury in subjects with ischemic heart disease. Paradoxically, reperfusion results in nitroxidative stress and a marked inflammatory response in the heart. TRAF3IP2 (TRAF3 Interacting Protein 2; previously known as CIKS or Act1...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Erikson, John M., Valente, Anthony J., Mummidi, Srinivas, Kandikattu, Hemanth Kumar, DeMarco, Vincent G., Bender, Shawn B., Fay, William P., Siebenlist, Ulrich, Chandrasekar, Bysani
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2017
Materias:
Molecular Bases of Disease
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5313105/
https://ncbi.nlm.nih.gov/pubmed/28053087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.764522
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