Stromal Interaction Molecule 1 (STIM1) Regulates ATP-sensitive Potassium (K(ATP)) and Store-operated Ca(2+) Channels in MIN6 β-Cells

Stromal interaction molecule 1 (STIM1) regulates store-operated Ca(2+) entry (SOCE) and other ion channels either as an endoplasmic reticulum Ca(2+)-sensing protein or when present in the plasma membrane. However, the role of STIM1 in insulin-secreting β-cells is unresolved. We report that lowering...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Leech, Colin A., Kopp, Richard F., Nelson, Heather A., Nandi, Jyotirmoy, Roe, Michael W.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2017
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5313099/
https://ncbi.nlm.nih.gov/pubmed/28003364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.767681
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