PML promotes metastasis of triple-negative breast cancer through transcriptional regulation of HIF1A target genes

Elucidating the molecular basis of tumor metastasis is pivotal for eradicating cancer-related mortality. Triple-negative breast cancer (TNBC) encompasses a class of aggressive tumors characterized by high rates of recurrence and metastasis, as well as poor overall survival. Here, we find that the pr...

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Veröffentlicht in:JCI Insight
Hauptverfasser: Ponente, Manfredi, Campanini, Letizia, Cuttano, Roberto, Piunti, Andrea, Delledonne, Giacomo A., Coltella, Nadia, Valsecchi, Roberta, Villa, Alessandra, Cavallaro, Ugo, Pattini, Linda, Doglioni, Claudio, Bernardi, Rosa
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5313064/
https://ncbi.nlm.nih.gov/pubmed/28239645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.87380
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