Effect of Radiosurgery Alone vs Radiosurgery With Whole Brain Radiation Therapy on Cognitive Function in Patients With 1 to 3 Brain Metastases: A Randomized Clinical Trial

IMPORTANCE: Whole brain radiotherapy (WBRT) significantly improves tumor control in the brain after stereotactic radiosurgery (SRS), yet because of its association with cognitive decline, its role in the treatment of patients with brain metastases remains controversial. OBJECTIVE: To determine wheth...

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Veröffentlicht in:JAMA
Hauptverfasser: Brown, Paul D., Jaeckle, Kurt, Ballman, Karla V., Farace, Elana, Cerhan, Jane H., Anderson, S. Keith, Carrero, Xiomara W., Barker, Fred G., Deming, Richard, Burri, Stuart H., Ménard, Cynthia, Chung, Caroline, Stieber, Volker W., Pollock, Bruce E., Galanis, Evanthia, Buckner, Jan C., Asher, Anthony L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5313044/
https://ncbi.nlm.nih.gov/pubmed/27458945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2016.9839
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