RNA-Seq analysis of chikungunya virus infection and identification of granzyme A as a major promoter of arthritic inflammation

Chikungunya virus (CHIKV) is an arthritogenic alphavirus causing epidemics of acute and chronic arthritic disease. Herein we describe a comprehensive RNA-Seq analysis of feet and lymph nodes at peak viraemia (day 2 post infection), acute arthritis (day 7) and chronic disease (day 30) in the CHIKV ad...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Principais autores: Wilson, Jane A. C., Prow, Natalie A., Schroder, Wayne A., Ellis, Jonathan J., Cumming, Helen E., Gearing, Linden J., Poo, Yee Suan, Taylor, Adam, Hertzog, Paul J., Di Giallonardo, Francesca, Hueston, Linda, Le Grand, Roger, Tang, Bing, Le, Thuy T., Gardner, Joy, Mahalingam, Suresh, Roques, Pierre, Bird, Phillip I., Suhrbier, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312928/
https://ncbi.nlm.nih.gov/pubmed/28207896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006155
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