Mucosal stromal fibroblasts markedly enhance HIV infection of CD4+ T cells

Understanding early events of HIV transmission within mucosal tissues is vital for developing effective prevention strategies. Here, we report that primary stromal fibroblasts isolated from endometrium, cervix, foreskin, male urethra, and intestines significantly increase HIV infection of CD4+ T cel...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Neidleman, Jason A., Chen, Joseph C., Kohgadai, Nargis, Müller, Janis A., Laustsen, Anders, Thavachelvam, Karthiga, Jang, Karen S., Stürzel, Christina M., Jones, Jennifer J., Ochsenbauer, Christina, Chitre, Avantika, Somsouk, Ma, Garcia, Maurice M., Smith, James F., Greenblatt, Ruth M., Münch, Jan, Jakobsen, Martin R., Giudice, Linda C., Greene, Warner C., Roan, Nadia R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312882/
https://ncbi.nlm.nih.gov/pubmed/28207890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006163
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