PARP-1 Expression Quantified by [(18)F]FluorThanatrace: A Biomarker of Response to PARP Inhibition Adjuvant to Radiation Therapy

Introduction: Poly (ADP-ribose) polymerase 1 (PARP-1) is the major target of clinical PARP inhibitors and is a potential predictive biomarker for response to therapy. Due to the limited success of PARP inhibitors as monotherapy, investigators have shifted the clinical role of PARP inhibitors to the...

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Bibliografiske detaljer
Udgivet i:Cancer Biother Radiopharm
Main Authors: Sander Effron, Samuel, Makvandi, Mehran, Lin, Lilie, Xu, Kuiying, Li, Shihong, Lee, Hsiaoju, Hou, Catherine, Pryma, Daniel A., Koch, Cameron, Mach, Robert H.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2017
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312613/
https://ncbi.nlm.nih.gov/pubmed/28118040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cbr.2016.2133
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