CD4-binding regions of human immunodeficiency virus envelope glycoprotein gp120 defined by proteolytic digestion.

The gp120 envelope glycoprotein of human immunodeficiency virus type 1 binds the cell surface protein CD4 with high affinity. Here we report the use of proteolysis to define regions of gp120 involved in CD4 binding. Cleavage of gp120 with Staphylococcus aureus V8 protease at residue 269 or with tryp...

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Main Authors: Pollard, S R, Meier, W, Chow, P, Rosa, J J, Wiley, D C
Formato: Artigo
Idioma:Inglês
Publicado: 1991
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC53126/
https://ncbi.nlm.nih.gov/pubmed/1763044
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