An integrative metabolomics and transcriptomics study to identify metabolic alterations in aged skin of humans in vivo

BACKGROUND: Aging human skin undergoes significant morphological and functional changes such as wrinkle formation, reduced wound healing capacity, and altered epidermal barrier function. Besides known age-related alterations like DNA-methylation changes, metabolic adaptations have been recently link...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Kuehne, Andreas, Hildebrand, Janosch, Soehle, Joern, Wenck, Horst, Terstegen, Lara, Gallinat, Stefan, Knott, Anja, Winnefeld, Marc, Zamboni, Nicola
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312537/
https://ncbi.nlm.nih.gov/pubmed/28201987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-3547-3
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