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Reduced DNA methylation patterning and transcriptional connectivity define human skin aging

Epigenetic changes represent an attractive mechanism for understanding the phenotypic changes associated with human aging. Age‐related changes in DNA methylation at the genome scale have been termed ‘epigenetic drift’, but the defining features of this phenomenon remain to be established. Human epid...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Bormann, Felix, Rodríguez‐Paredes, Manuel, Hagemann, Sabine, Manchanda, Himanshu, Kristof, Boris, Gutekunst, Julian, Raddatz, Günter, Haas, Rainer, Terstegen, Lara, Wenck, Horst, Kaderali, Lars, Winnefeld, Marc, Lyko, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854925/
https://ncbi.nlm.nih.gov/pubmed/27004597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12470
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