IL-2 augments the therapeutic efficacy of adoptively transferred B cells which directly kill tumor cells via the CXCR4/CXCL12 and perforin pathways

We previously reported that antitumor B cells directly kill tumor cells via the Fas/FasL pathway and are regulated by IL-10. In this study, we defined additional mechanisms involved in B cell antitumor immunity. Administration of IL-2 significantly augmented the therapeutic efficacy of adoptively tr...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Xia, Yang, Tao, Huimin, Hu, Yangyang, Chen, Quanning, Chen, Xin, Xia, Leiming, Zhou, Li, Wang, Yi, Bao, Yangyi, Huang, Shiang, Ren, Xiubao, Lundy, Steven K., Dai, Fu, Li, Qiao, Chang, Alfred E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2016
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312396/
https://ncbi.nlm.nih.gov/pubmed/27528023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11124
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