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The interplay between the lysine demethylase KDM1A and DNA methyltransferases in cancer cells is cell cycle dependent

DNA methylation and histone modifications are key epigenetic regulators of gene expression, and tight connections are known between the two. DNA methyltransferases are upregulated in several tumors and aberrant DNA methylation profiles are a cancer hallmark. On the other hand, histone demethylases a...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Brenner, Carmen, Luciani, Judith, Bizet, Martin, Ndlovu, Matladi, Josseaux, Eleonore, Dedeurwaerder, Sarah, Calonne, Emilie, Putmans, Pascale, Cartron, Pierre-Francois, Defrance, Matthieu, Fuks, François, Deplus, Rachel
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312287/
https://ncbi.nlm.nih.gov/pubmed/27449289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10624
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