The interplay between the lysine demethylase KDM1A and DNA methyltransferases in cancer cells is cell cycle dependent

DNA methylation and histone modifications are key epigenetic regulators of gene expression, and tight connections are known between the two. DNA methyltransferases are upregulated in several tumors and aberrant DNA methylation profiles are a cancer hallmark. On the other hand, histone demethylases a...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Brenner, Carmen, Luciani, Judith, Bizet, Martin, Ndlovu, Matladi, Josseaux, Eleonore, Dedeurwaerder, Sarah, Calonne, Emilie, Putmans, Pascale, Cartron, Pierre-Francois, Defrance, Matthieu, Fuks, François, Deplus, Rachel
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312287/
https://ncbi.nlm.nih.gov/pubmed/27449289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10624
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