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C/EBP-Induced Transdifferentiation Reveals Granulocyte-Macrophage Precursor-like Plasticity of B Cells

The lymphoid-myeloid transdifferentiation potentials of members of the C/EBP family (C/EBPα, β, δ, and ε) were compared in v-Abl-immortalized primary B cells. Conversion of B cells to macrophages was readily induced by the ectopic expression of any C/EBP, and enhanced by endogenous C/EBPα and β acti...

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Publicat a:Stem Cell Reports
Autors principals: Cirovic, Branko, Schönheit, Jörg, Kowenz-Leutz, Elisabeth, Ivanovska, Jelena, Klement, Christine, Pronina, Nina, Bégay, Valérie, Leutz, Achim
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312250/
https://ncbi.nlm.nih.gov/pubmed/28111277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.12.015
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