Recapitulation of Clinical Individual Susceptibility to Drug-Induced QT Prolongation in Healthy Subjects Using iPSC-Derived Cardiomyocytes

To predict drug-induced serious adverse events (SAE) in clinical trials, a model using a panel of cells derived from human induced pluripotent stem cells (hiPSCs) of individuals with different susceptibilities could facilitate major advancements in translational research in terms of safety and pharm...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Stem Cell Reports
Egile Nagusiak: Shinozawa, Tadahiro, Nakamura, Koki, Shoji, Masanobu, Morita, Maya, Kimura, Maya, Furukawa, Hatsue, Ueda, Hiroki, Shiramoto, Masanari, Matsuguma, Kyoko, Kaji, Yoshikazu, Ikushima, Ippei, Yono, Makoto, Liou, Shyh-Yuh, Nagai, Hirofumi, Nakanishi, Atsushi, Yamamoto, Keiji, Izumo, Seigo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2017
Gaiak:
Report
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312248/
https://ncbi.nlm.nih.gov/pubmed/28111276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.12.014
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