Phosphoribosyl Diphosphate (PRPP): Biosynthesis, Enzymology, Utilization, and Metabolic Significance

Phosphoribosyl diphosphate (PRPP) is an important intermediate in cellular metabolism. PRPP is synthesized by PRPP synthase, as follows: ribose 5-phosphate + ATP → PRPP + AMP. PRPP is ubiquitously found in living organisms and is used in substitution reactions with the formation of glycosidic bonds....

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Vydáno v:Microbiol Mol Biol Rev
Hlavní autoři: Hove-Jensen, Bjarne, Andersen, Kasper R., Kilstrup, Mogens, Martinussen, Jan, Switzer, Robert L., Willemoës, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312242/
https://ncbi.nlm.nih.gov/pubmed/28031352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MMBR.00040-16
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