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Escherichia coli phnN, Encoding Ribose 1,5-Bisphosphokinase Activity (Phosphoribosyl Diphosphate Forming): Dual Role in Phosphonate Degradation and NAD Biosynthesis Pathways

An enzymatic pathway for synthesis of 5-phospho-d-ribosyl α-1-diphosphate (PRPP) without the participation of PRPP synthase was analyzed in Escherichia coli. This pathway was revealed by selection for suppression of the NAD requirement of strains with a deletion of the prs gene, the gene encoding PR...

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Detalhes bibliográficos
Main Authors: Hove-Jensen, Bjarne, Rosenkrantz, Tina J., Haldimann, Andreas, Wanner, Barry L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC154390/
https://ncbi.nlm.nih.gov/pubmed/12700258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.9.2793-2801.2003
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