Escherichia coli phnN, Encoding Ribose 1,5-Bisphosphokinase Activity (Phosphoribosyl Diphosphate Forming): Dual Role in Phosphonate Degradation and NAD Biosynthesis Pathways

An enzymatic pathway for synthesis of 5-phospho-d-ribosyl α-1-diphosphate (PRPP) without the participation of PRPP synthase was analyzed in Escherichia coli. This pathway was revealed by selection for suppression of the NAD requirement of strains with a deletion of the prs gene, the gene encoding PR...

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Detalles Bibliográficos

Publicado en:	J Bacteriol
Autores principales:	Hove-Jensen, Bjarne, Rosenkrantz, Tina J., Haldimann, Andreas, Wanner, Barry L.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2003
Materias:	Physiology and Metabolism
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154390/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12700258/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.185.9.2793-2801.2003
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