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Meningeal retinoic acid contributes to neocortical lamination and radial migration during mouse brain development

Retinoic acid (RA) is a diffusible molecule involved in early forebrain patterning. Its later production in the meninges by the retinaldehyde dehydrogenase RALDH2 coincides with the time of cortical neuron generation. A function of RA in this process has not been adressed directly as Raldh2(−/−) mou...

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Détails bibliographiques
Publié dans:Biol Open
Auteurs principaux: Haushalter, Carole, Schuhbaur, Brigitte, Dollé, Pascal, Rhinn, Muriel
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312094/
https://ncbi.nlm.nih.gov/pubmed/28011626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.021063
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