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FANCD2 Binds Human Papillomavirus Genomes and Associates with a Distinct Set of DNA Repair Proteins to Regulate Viral Replication

The life cycle of human papillomavirus (HPV) is dependent on the differentiation state of its host cell. HPV genomes are maintained as low-copy episomes in basal epithelial cells and amplified to thousands of copies per cell in differentiated layers. Replication of high-risk HPVs requires the activa...

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Bibliographic Details
Published in:mBio
Main Authors: Spriggs, Chelsey C., Laimins, Laimonis A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312087/
https://ncbi.nlm.nih.gov/pubmed/28196964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02340-16
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