Genome editing reveals dmrt1 as an essential male sex-determining gene in Chinese tongue sole (Cynoglossus semilaevis)

Chinese tongue sole is a marine fish with ZW sex determination. Genome sequencing suggested that the Z-linked dmrt1 is a putative male determination gene, but direct genetic evidence is still lacking. Here we show that TALEN of dmrt1 efficiently induced mutations of this gene. The ZZ dmrt1 mutant fi...

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Publicat a:Sci Rep
Autors principals: Cui, Zhongkai, Liu, Yun, Wang, Wenwen, Wang, Qian, Zhang, Ning, Lin, Fan, Wang, Na, Shao, Changwei, Dong, Zhongdian, Li, Yangzhen, Yang, Yingming, Hu, Mengzhu, Li, Hailong, Gao, Fengtao, Wei, Zhanfei, Meng, Liang, Liu, Yang, Wei, Min, Zhu, Ying, Guo, Hua, Cheng, Christopher H. K., Schartl, Manfred, Chen, Songlin
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5311979/
https://ncbi.nlm.nih.gov/pubmed/28205594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42213
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