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Inhibition of HIV-1 Gag–membrane interactions by specific RNAs
HIV-1 particle assembly, which occurs at the plasma membrane (PM) of cells, is driven by the viral polyprotein Gag. Gag recognizes phosphatidylinositol-(4,5)-bisphosphate [PI(4,5)P(2)], a PM-specific phospholipid, via the highly basic region (HBR) in its N-terminal matrix (MA) domain. The HBR is als...
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| Publicado no: | RNA |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5311501/ https://ncbi.nlm.nih.gov/pubmed/27932583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.058453.116 |
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