Effect of tcdR Mutation on Sporulation in the Epidemic Clostridium difficile Strain R20291

Clostridium difficile is an important nosocomial pathogen and the leading cause of hospital-acquired diarrhea. Antibiotic use is the primary risk factor for the development of C. difficile-associated disease because it disrupts normally protective gut flora and enables C. difficile to colonize the c...

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Udgivet i:mSphere
Main Authors: Girinathan, Brintha P., Monot, Marc, Boyle, Daniel, McAllister, Kathleen N., Sorg, Joseph A., Dupuy, Bruno, Govind, Revathi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5311115/
https://ncbi.nlm.nih.gov/pubmed/28217744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00383-16
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