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Characterization of the SigD Regulon of C. difficile and Its Positive Control of Toxin Production through the Regulation of tcdR

Clostridium difficile intestinal disease is mediated largely by the actions of toxins A (TcdA) and B (TcdB), whose production occurs after the initial steps of colonization involving different surface or flagellar proteins. In B. subtilis, the sigma factor SigD controls flagellar synthesis, motility...

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Autors principals: El Meouche, Imane, Peltier, Johann, Monot, Marc, Soutourina, Olga, Pestel-Caron, Martine, Dupuy, Bruno, Pons, Jean-Louis
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865298/
https://ncbi.nlm.nih.gov/pubmed/24358307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083748
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