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The Second Messenger Cyclic Di-GMP Regulates Clostridium difficile Toxin Production by Controlling Expression of sigD

The Gram-positive obligate anaerobe Clostridium difficile causes potentially fatal intestinal diseases. How this organism regulates virulence gene expression is poorly understood. In many bacterial species, the second messenger cyclic di-GMP (c-di-GMP) negatively regulates flagellar motility and, in...

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Bibliografski detalji
Glavni autori: McKee, Robert W., Mangalea, Mihnea R., Purcell, Erin B., Borchardt, Erin K., Tamayo, Rita
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811590/
https://ncbi.nlm.nih.gov/pubmed/24039264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00501-13
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