A Nutrient-Regulated Cyclic Diguanylate Phosphodiesterase Controls Clostridium difficile Biofilm and Toxin Production during Stationary Phase

The signaling molecule cyclic diguanylate (c-di-GMP) mediates physiological adaptation to extracellular stimuli in a wide range of bacteria. The complex metabolic pathways governing c-di-GMP synthesis and degradation are highly regulated, but the specific cues that impact c-di-GMP signaling are larg...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Purcell, Erin B., McKee, Robert W., Courson, David S., Garrett, Elizabeth M., McBride, Shonna M., Cheney, Richard E., Tamayo, Rita
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563577/
https://ncbi.nlm.nih.gov/pubmed/28652311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00347-17
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