Systemic administration of cell-free exosomes generated by human bone marrow derived mesenchymal stem cells cultured under 2D and 3D conditions improves functional recovery in rats after traumatic brain injury

Multipotent human bone marrow derived mesenchymal stem cells (hMSCs) improve functional outcome after experimental traumatic brain injury (TBI). The present study was designed to investigate whether systemic administration of cell-free exosomes generated from hMSCs cultured in 2-dimensional (2D) con...

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Publicado en:Neurochem Int
Autores principales: Zhang, Yanlu, Chopp, Michael, Zhang, Zheng Gang, Katakowski, Mark, Xin, Hongqi, Qu, Changsheng, Ali, Meser, Mahmood, Asim, Xiong, Ye
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5311054/
https://ncbi.nlm.nih.gov/pubmed/27539657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2016.08.003
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