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Effect of exosomes derived from multipluripotent mesenchymal stromal cells on functional recovery and neurovascular plasticity in rats after traumatic brain injury

OBJECT: Transplanted multipotent mesenchymal stromal cells (MSCs) improve functional recovery in rats after traumatic brain injury (TBI). Here, we test a novel hypothesis that systemic administration of cell-free exosomes generated from MSCs promotes functional recovery and neurovascular remodeling...

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Detalhes bibliográficos
Publicado no:J Neurosurg
Main Authors: Zhang, Yanlu, Chopp, Michael, Meng, Yuling, Katakowski, Mark, Xin, Hongqi, Mahmood, Asim, Xiong, Ye
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382456/
https://ncbi.nlm.nih.gov/pubmed/25594326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/2014.11.JNS14770
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