Fingolimod Confers Neuroprotection through Activation of Rac1 after Experimental Germinal Matrix Hemorrhage in Rat Pups

Fingolimod, a sphingosine-1-phosphate receptor (S1PR) agonist, is clinically available to treat multiple sclerosis and is showing promise in treating stroke. We investigated if fingolimod provides long-term protection from experimental neonatal germinal matrix hemorrhage (GMH), aiming to support a p...

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Bibliografiset tiedot
Julkaisussa:J Neurochem
Päätekijät: Rolland, William B., Krafft, Paul R., Lekic, Tim, Klebe, Damon, LeGrand, Julia, Weldon, Abby Jones, Xu, Liang, Zhang, John H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5311019/
https://ncbi.nlm.nih.gov/pubmed/28054340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13946
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