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Mathematical Modeling of Mutant Transferrin-CRM107 Molecular Conjugates for Cancer Therapy
The transferrin (Tf) trafficking pathway is a promising mechanism for use in targeted cancer therapy due to the overexpression of transferrin receptors (TfRs) on cancerous cells. We have previously developed a mathematical model of the Tf/TfR trafficking pathway to improve the efficiency of Tf as a...
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| Publicado no: | J Theor Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5310938/ https://ncbi.nlm.nih.gov/pubmed/28065783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2017.01.008 |
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