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Sensitivity to restimulation-induced cell death is linked to glycolytic metabolism in human T cells

Restimulation-induced cell death (RICD) regulates immune responses by restraining effector T cell expansion and limiting nonspecific damage to the host. RICD is triggered by re-engagement of the T cell receptor (TCR) on a cycling effector T cell, resulting in apoptosis. It remains unclear how RICD s...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Larsen, Sasha E., Bilenkin, Abegail, Tarasenko, Tatiana N., Arjunaraja, Swadhinya, Stinson, Jeffrey R., McGuire, Peter J., Snow, Andrew L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5310646/
https://ncbi.nlm.nih.gov/pubmed/27852741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601218
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