Fatty Acid Synthase Contributes to Restimulation-Induced Cell Death of Human CD4 T Cells

Restimulation-induced cell death (RICD) is an apoptotic pathway triggered in activated effector T cells after T cell receptor (TCR) re-engagement. RICD operates at the peak of the immune response to ensure T cell expansion remains in check to maintain immune homeostasis. Understanding the biochemica...

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Main Authors: Kelsey Voss, Christopher R. Luthers, Katherine Pohida, Andrew L. Snow
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019-10-01
Colecção:Frontiers in Molecular Biosciences
Assuntos:
T cell
RICD
apoptosis
metabolism
fatty acid synthase
glycolysis
Acesso em linha:https://www.frontiersin.org/article/10.3389/fmolb.2019.00106/full
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