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Evolutionary adaptation of the sensitivity of connexin26 hemichannels to CO(2)

CO(2) readily combines with H(2)O to form [Image: see text] and H(+). Because an increase of only 100 nM in the concentration of H(+) (a decrease of 0.1 unit of pH) in blood can prove fatal, the regulated excretion of CO(2) during breathing is an essential life-preserving process. In rodents and hum...

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Detalhes bibliográficos
Publicado no:Proc Biol Sci
Main Authors: de Wolf, Elizabeth, Cook, Jonathan, Dale, Nicholas
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5310615/
https://ncbi.nlm.nih.gov/pubmed/28148750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2016.2723
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