An S116R Phosphorylation Site Mutation in Human Fibroblast Growth Factor-1 Differentially Affects Mitogenic and Glucose-Lowering Activities

Fibroblast growth factor-1 (FGF-1), a potent human mitogen and insulin sensitizer, signals through both tyrosine kinase receptoremediated autocrine/paracrine pathways as well as a nuclear intracrine pathway. Phosphorylation of FGF-1 at serine 116 (S116) has been proposed to regulate intracrine signa...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Pharm Sci
Main Authors: Xia, Xue, Kumru, Ozan S., Blaber, Sachiko I., Middaugh, C. Russell, Li, Ling, Ornitz, David M., Suh, Jae Myoung, Atkins, Annette R., Downes, Michael, Evans, Ronald M., Tenorio, Connie A., Bienkiewicz, Ewa, Blaber, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5310217/
https://ncbi.nlm.nih.gov/pubmed/27773526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2016.09.005
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados