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A single aromatic core mutation converts a designed “primitive” protein from halophile to mesophile folding

The halophile environment has a number of compelling aspects with regard to the origin of structured polypeptides (i.e., proteogenesis) and, instead of a curious niche that living systems adapted into, the halophile environment is emerging as a candidate “cradle” for proteogenesis. In this viewpoint...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Longo, Liam M, Tenorio, Connie A, Kumru, Ozan S, Middaugh, C Russell, Blaber, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282409/
https://ncbi.nlm.nih.gov/pubmed/25297559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2580
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