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A single aromatic core mutation converts a designed “primitive” protein from halophile to mesophile folding
The halophile environment has a number of compelling aspects with regard to the origin of structured polypeptides (i.e., proteogenesis) and, instead of a curious niche that living systems adapted into, the halophile environment is emerging as a candidate “cradle” for proteogenesis. In this viewpoint...
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Publicado no: | Protein Sci |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Blackwell Publishing Ltd
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4282409/ https://ncbi.nlm.nih.gov/pubmed/25297559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2580 |
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