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Acyl Ghrelin Induces Insulin Resistance Independently of GH, Cortisol, and Free Fatty Acids

Ghrelin produced in the gut stimulates GH and ACTH secretion from the pituitary and also stimulates appetite and gastric emptying. We have shown that ghrelin also induces insulin resistance via GH-independent mechanisms, but it is unknown if this effect depends on ambient fatty acid (FFA) levels. We...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Vestergaard, Esben T., Jessen, Niels, Møller, Niels, Jørgensen, Jens Otto Lunde
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309923/
https://ncbi.nlm.nih.gov/pubmed/28198428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42706
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