Ghrelin Infusion in Humans Induces Acute Insulin Resistance and Lipolysis Independent of Growth Hormone Signaling

OBJECTIVE—Ghrelin is a gut-derived peptide and an endogenous ligand for the growth hormone (GH) secretagogue receptor. Exogenous ghrelin stimulates the release of GH (potently) and adrenocorticotropic hormone (ACTH) (moderately). Ghrelin is also orexigenic, but its impact on substrate metabolism is...

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Autores principales: Vestergaard, Esben Thyssen, Gormsen, Lars Christian, Jessen, Niels, Lund, Sten, Hansen, Troels Krarup, Moller, Niels, Jorgensen, Jens Otto Lunde
Formato: Artigo
Lenguaje:Inglês
Publicado: American Diabetes Association 2008
Materias:
Metabolism
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584125/
https://ncbi.nlm.nih.gov/pubmed/18776138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0025
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