Ghrelin Infusion in Humans Induces Acute Insulin Resistance and Lipolysis Independent of Growth Hormone Signaling

OBJECTIVE—Ghrelin is a gut-derived peptide and an endogenous ligand for the growth hormone (GH) secretagogue receptor. Exogenous ghrelin stimulates the release of GH (potently) and adrenocorticotropic hormone (ACTH) (moderately). Ghrelin is also orexigenic, but its impact on substrate metabolism is...

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Detalhes bibliográficos
Main Authors: Vestergaard, Esben Thyssen, Gormsen, Lars Christian, Jessen, Niels, Lund, Sten, Hansen, Troels Krarup, Moller, Niels, Jorgensen, Jens Otto Lunde
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2008
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584125/
https://ncbi.nlm.nih.gov/pubmed/18776138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0025
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